In discussions of gene-environment interactions, children who carry the minor allele for the GSTP1 SNPs rs1138272 or rs1695 (Ile105Val), plus exposure to NO2 using land use regression and dispersion modelling have greater susceptibility to injury from air pollution in comparison to major allele carriers, and this susceptibility is highest in children with current asthma, ever asthma, and ever wheeze [131,132]. Here, GSTP1 is linked to asthma.