BAZ2A and B-cell chronic lymphocytic leukemia: One study found that MIR-15a/16-1 at chromosome band 13q14 is downregulated in most patients with chronic lymphocytic leukemia (CLL), and by comparing the expression of MIR-15a/16-1 and computationally predicted MIR-15 a/16-1 target genes in CLL patients and normal controls, BAZ2A was identified as the MIR-15a/16-1 specific target gene, and BAZ2A was significantly upregulated in CLL patients with MIR-15a/16-1 expression (p < 0.05) [68].