This was consistent with the findings of Bennett et al. [28], which showed that OPG in serum decreased, bone formation decreased, and bone resorption increased, when OPG was elevated, bone formation increased, bone resorption decreased, and bone increased, and the results indicated that CHF and BPs have bone-enhancing effects. The gene discussed is TNFRSF11B; the disease is Bartsocas-Papas syndrome 1.