In the same experimental group at different ages: the relative expression of RANKL mRNA in thoracic vertebra tissue at 30 days of age in both CHF and BPs groups was lower than that at 60 days of age, the BPs-L group was significantly lower at the age of 30 days than at the age of 60 days (p < 0.05). The gene discussed is TNFSF11; the disease is Bartsocas-Papas syndrome 1.