Between different experimental groups at the same age: for 30 days of age, the relative expression of Runx-2 mRNA in the thoracic vertebra tissue of the CHF and BPs groups was higher than that of the control NC group, and the relative expression of Runx-2 mRNA in thoracic vertebra tissue of the BPs-H group was significantly higher than CHF-L, BPs-L group (p < 0.05), CHF-M group was significantly higher than CHF-L group (p < 0.05). This evidence concerns the gene RUNX2 and Bartsocas-Papas syndrome 1.