In the same experimental group at different ages: in the CHF group and BPs-H, BPs-L groups all 30-day-old leg cartilage tissue relative expression of RANK mRNA was lower than 60-day-old, and the 30-day age of the BPs-H group was significantly lower than that of the 60-day age (p < 0.05). Here, TNFRSF11A is linked to congestive heart failure.