Between different experimental groups at the same age: for 30 days of age, the relative expression of Runx-2 mRNA in leg cartilage tissue of the CHF and BPs groups was higher than that of the NC group, and the BPs-H group was significantly higher than that of the BPs-M group (p < 0.05). Here, RUNX2 is linked to Bartsocas-Papas syndrome 1.