In this experiment, in the thoracic vertebrae and leg cartilage tissues, the relative expression levels of BMP-2 mRNA in the thoracic vertebrae of the CHF and BPs groups were higher than those of the NC group at 30 and 60 days of age, and the relative expression of BMP-2 mRNA in the CHF-H group was only lower than that in BPs-H and BPs-M groups. The gene discussed is BMP2; the disease is congestive heart failure.