One genome-wide significant lead SNP (rs10457469, near HEY2) from the cross-trait meta-analysis of migraine and T2D was not novel (Supplementary Table S5) as, although it was genome-wide suggestive in the individual migraine GWAS, it was genome-wide significant in the individual T2D GWAS [17]. The gene discussed is HEY2; the disease is migraine disorder.