However, we only discovered that the low expression of LI1RN was correlated with the worse OS; the high expression of nine genes was associated with worse OS in the HCC patients including BIRC5, CDK4, DCK, HSP90AA1, HSPA4, PGF, PSMD2, SPP1, and STC2 (Figure 4E,F). Here, SPP1 is linked to hepatocellular carcinoma.