Finally, the expression of C11orf31 was significantly higher in FXS-ASD subjects (n = 16) compared to TD (n = 8, p = 0.04) or ASD (n = 16, p = 0.02), which also agreed with the CpG hypomethylated status observed in children with FXS-ASD compared to ASD and TD subjects. The gene discussed is SELENOH; the disease is fragile X syndrome.