In order to find novel matching anticancer drugs for the above-mentioned malignant tumors, we analyzed the FOX genes in Figure S1 and Figure 8A. As shown in Figure 8D, the expression of FOXJ2, FOXN2, FOXN3, and FOXO3, which were originally highly expressed in AML, was suppressed after the stimulation of MTX. This evidence concerns the gene FOXO3 and acute myeloid leukemia.