BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Chronic myeloid leukemia (CML) is a neoplasm disorder derived from stem cells and characterized by the Philadelphia (Ph) chromosome, developedafter a reciprocal translation between chromosomes 9 and 22, which leads to the hybridization of the BCR (breakpoint cluster region) and ABL (Abelson oncogene locus) [1].