Thus, the present study, in relation to the individual previous studies, aims to identify SPA17, PPP1R36, AURKA, TRIP13, PLK4, CCDC90B, and CCDC91 genes as important biomarkers of both teratozoospermia- and azoospermia-associated infertility in men. The gene discussed is PLK4; the disease is Abnormal sperm morphology.