LOX and myocardial infarction: In a primate model of myocardial infarction (MI), Xiao et al. (2016) observed a marked increase in LOX mRNA and LOX activity, with an accumulation of LOX protein in the myofibroblasts, endothelial cells, and residual cardiomyocytes associated with enhanced collagen type I and III depositions in the infarcted area [128].