MiR-29b-3p has a significant role in CHD since its serum level was two-fold higher in patients with frank CHD compared to healthy subjects (p = 0.05) [202], probably by promoting coronary atherosclerosis via ANGPTL4 silencing in the macrophage causing enhanced monocytic migration and foam cell formation within the affected vessel. This evidence concerns the gene ANGPTL4 and coronary atherosclerosis.