There were no statistical significances in age (p = 0.372), gender (p = 0.359), operation type (p = 0.586), differentiation (p = 0.19), EGFR mutation (p = 0.196), location (p = 0.633), smoking habits (p = 0.522), lymphovascular space invasion (LVSI) (p = 0.289), VPI (p = 0.348), pathologic stages (p = 0.72), tumor size (p = 0.373), carcinoembryonic antigen (CEA) (p = 0.67) and GGO ratio (p = 0.443). This evidence concerns the gene EGFR and neoplasm.