Multiple candidate genes (DEFB1, FGFR1, FGFR3, ESRRB, FGF10, MMP-1, TNC, FCRL3, SASH1, SA30BP) and rs71404070 located next to cadherin8 have been implicated in rotator cuff tears [4]. The gene discussed is MMP1; the disease is rotator cuff syndrome.