In spinal cord injury (SCI), Yin et al. found that circHIPK3 was sharply diminished in SCI cell models and circHIPK3 overexpression attenuated inflammation and neuron death by downregulating miR-382-5p and then strengthened dual specificity phosphatase 1 (DUSP1) expression [118]. The gene discussed is DUSP1; the disease is spinal cord injury.