Ki-67 index levels were significantly positively correlated with the size (p < 0.001, r = 0.69), the cavernous sinus invasion of the PAs (based on Knosp’s classification) (p < 0.001, r = 0.37), the extrasellar invasion (based of Hardy’s classification) (p = < 0.001, r = 0.4) and with PAs’ recurrence (p = 0.007 r = 0.3) (Figure 3). The gene discussed is MKI67; the disease is gonorrhea.