CD274 and Hodgkins lymphoma: Among clinical parameters, the International Prognostic Score for Hodgkin’s Lymphoma (IPS) is widely used, especially in patients with an advanced stage at diagnosis [2]; recently, programmed death ligand 1 (PD-L1) expression on peripheral-blood granulocytes has also been proposed as a prognostic factor in newly diagnosed HL [3], but larger studies are needed to avail its use in clinical practice.