Univariate Cox analysis showed that the presence of TLSs, aspartate transaminase (AST), lymph, alkaline phosphatase (ALP), albumin (ALB), tumour diameter, tumour capsule, cancer emboli, Child grade, American Joint Committee on Cancer (AJCC) stage and Barcelona Clinic Liver Cancer (BCLC) stage were significantly correlated with RFS. This evidence concerns the gene ALB and neoplasm.