EGFR and cancer: For example, Seifert and colleagues [211] engineered liposomes able to target epidermal growth factor receptor (EGFR, overexpressed on a variety of cancers) [212,213] by functionalizing the liposomes with an EGFR-specific single-chain Fv molecule (EGFR scFv) and TRAIL (immune-LipoTRAIL) [211].