To determine if SDHA overexpression redirects cellular metabolism in response to nutrient deprivation, we cultured selected ovarian cancer cell lines in low glucose, low glutamine or galactose medium (where glucose was replaced with galactose) and assessed cellular respiration by the Seahorse XF Cell Mito Stress Test (Figure 7A–D and Figure S3A–H). The gene discussed is SDHA; the disease is ovarian cancer.