In the first multivariable Cox regression analysis model using the original ABLI grade (Model 1), AFP (≥400 ng/mL), tumor size, MVI, and ALBI grade (hazard ratio (HR): 2.370, 95% CI: 2.074–2.708, p < 0.001 for grade 2 vs. 1; HR 1.771, 95% CI: 1.323–2.370, p < 0.001 for grade 3 vs. 2) were independent predictors of OS in the enrolled patients. This evidence concerns the gene AFP and neoplasm.