MTOR and Miyoshi myopathy: The most recent studies consistently demonstrate that the presence of biologically functional genetic polymorphisms in mTOR-related genes, such as ULK4, ATG5, and WAC, or in genes related to IRF4–MYC-dependent autophagy, such as CDCA7L, DNMT3A, CBX7, and KLF2, is strongly associated with the risk of developing MM [231].