These findings have been corroborated, in breast cancer cohorts, by finding that downregulation of RKIP appears to be proportionally related to increased expression of SNAIL 1, BACH1 and some other EMT markers such as vimentin and Zinc Finger E-Box Binding Homeobox 1/2—ZEB1/2 [10]. The gene discussed is ZEB1; the disease is breast cancer.