TERT and meningioma: Recent papers have indicated a possibility of improved delineation of phenotypes with the addition of molecular markers and a novel molecular classification has been proposed by Driver et al. [29] and Sahm et al. [30] For example, it has been shown that RNA profiles in WHO grade 1 meningiomas differ between tumors undergoing malignant transformation and those that do not [31], and that TERT-promotor mutations mark a significant worsening of the prognosis [32].