KLK3 and posterior cortical atrophy: In this setting, very recently, the European Health Union proposed a new approach on cancer detection, introducing the proposal of a regular systematic monitoring of screening programs in order to cover in the future more target groups and more neoplasms; in particular for PCa, the recommendation is testing in men up to 70 on the basis of PSA level and magnetic resonance imaging (MRI) scanning as follow-up [4].