In addition, mutations in TP53, CDKN2A, APC, RICTOR, KMT2C, ERBB2, RB1, and EGFR appear to be associated with a high GI status of MM, as they have a high mutation frequency in the GI group, and patients with TP53 mutations had higher GI scores. This evidence concerns the gene KMT2C and Miyoshi myopathy.