NFKB1 and mycosis fungoides: Interesting hotspot point mutations in other oncogenes from this pathway such as NFKB1 (p.H67Y), KLF2 (p.H346Q/N/Y), and JUNB (p.A282V) and damaging mutations in the tumor suppressor genes FUBP1 and ANO6 have been newly identified in a large number of samples from diverse MF/SS stages [26,29].