Furthermore, GEPIA2 revealed that poor overall survival in ACC, BLCA, GBM, KIRP, LGG, LUAD, and SARC was significantly associated with high HSP90B1 expression; however, in ACC, BLCA, CHOL, KIRC, KIRP, LUAD, LUSC, and UVM, poor disease-free survival was significantly correlated with high HSP90B1 expression. Here, HSP90B1 is linked to adrenal cortex carcinoma.