CDH2 and neoplasm: E- and N-Cadherin mostly have mutually exclusive expression patterns, with E-Cadherin being expressed primarily in epithelial cells; however, in the context of EMT, N-Cadherin can induce changes in the biological behaviour of cells in favour of the migratory phenotype, and the ability of tumour cells to alter their cadherin expression profiles, such as transitioning from E- to N-cadherin, is critical for malignant progression [84,85,86].