PGP and cancer: The authors found that a combination of low concentrations of loratadine and fluphenazine could successfully sensitize eribulin-resistant KBV20C cells and that co-treatment with 5 μM of fluphenazine with eribulin had a similar effect as a combined treatment of vincristine + fluphenazine, suggesting low doses of this drug can be used in combined approaches with chemotherapeutic drugs to increase chemosensitization, especially in P-gp overexpressing cancer cells [56].