Indeed, it was more recently demonstrated that ABCC8 is expressed in lungs of healthy individuals and patients with PAH via reverse transcriptase polymerase chain reaction (RT-PCR) and that SUR1 protein, using immunohistochemistry, exhibited strong staining in alveolar macrophages and moderate staining in proximal pulmonary arteries of lung samples from patients with idiopathic PAH [12]. The gene discussed is ABCC8; the disease is pulmonary arterial hypertension.