Despite previous studies suggesting that CCL2 and CCL4 may have a significant effect on seizure control, which showed elevated levels of chemokines in patients with drug-resistant epilepsy [65], especially in temporal lobe epilepsy [66], as well as recent findings showing that the expression of these chemokines and their receptors in various CNS cells is relevant to psychiatric disorders [67], we were unable to detect alterations of CCL2 and CCL4 levels in our cohort. Here, CCL2 is linked to psychiatric disorder.