Crude p62 levels were significantly increased in FTD patients when compared to controls (0.97 ± 0.99 ng/mL vs. 0.15 ± 0.33 ng/mL, p < 0.001) (Figure 1), which persisted after adjusting for age (p = 0.008). This evidence concerns the gene SQSTM1 and frontotemporal dementia.