In view of a series of research above indicating that the NGFR gene may be closely related to the pathogenesis of psychiatric disorders such as depression and schizophrenia, we performed an association study of the Chinese Han population to investigate the role of the four NGFR SNPs (rs575791, rs1035050, rs2072446, rs11466162, Table 1) in schizophrenia and MDD. The gene discussed is NGFR; the disease is depressive symptom measurement.