Li et al. (2021) have also reported the creation of an hiPSC line from a patient carrying a mutation in the X-linked Apoptosis-Inducing Factor Mitochondria associated 1 (AIFM1) gene [106]; a large number of mutations have been identified in the AIFM1 gene that are associated with late-onset auditory neuropathies, characterized by impaired speech perception [107]. This evidence concerns the gene AIFM1 and auditory neuropathy.