SLC26A4 and deafness: Although no progressive deafness is observed in any of the rodent models for PDS [9], a degenerative phenotype has been described by Hosoya and colleagues on outer sulcus cell (OSC)-like cells derived from hiPSCs generated from PDS patients with mutated Pendrin/SLC26A4 (Solute Carrier Family 26 Member 4) alleles [36].