GJB2 and Hodgkins lymphoma: Mutations in the gap junction beta 2 (GJB2) gene, which codes for the connexin 26 (CX26) protein, are responsible for a very large proportion of the cases of non-syndromic HL in the world; this protein is found in gap junction channels in various non-sensory cell types in the cochlea, and it plays a role in K+ recycling and cochlear homeostasis.