In this context, a subtype of human ST anaplastic ependymomas (grade 3) called RELA fusion ependymomas (the fusion is called ZFTA-RELA, comprising the gene c11orf95, recently designed as ZFTA, and the gene encoding the main effector of canonical NF-κB signaling), representing about 60–70% of tumors that grow at the level of the lateral ventricles, were shown to present a chomothripsis event in a region of chromosome 11 (segments 11q12.1-11q13.3) where the IIIG9 gene (locus 11q12.2 for C11orf66) is found. The gene discussed is SAXO4; the disease is ependymoma.