Thus, these data lead us to speculate that, even though the mechanism of cell death may be the result of the absence of IIIG9 expression in the differentiated adult ependyma, under the tumorigenic context of the development of ST ependymomas, IIIG9 loss of function may be an event that promotes the lack of cell adhesion and the dissemination of these tumor cells frequently observed in this type of tumor. This evidence concerns the gene SAXO4 and ependymoma.