However, receptor expression for TNFSF10 is increased in IPF AECI (TNFRSF10B, average log2 fold-change 0.3659; TNFRSF10C, average log2 fold-change 0.4428) supporting a role for TNFSF10 signaling. This evidence concerns the gene TNFRSF10C and idiopathic pulmonary fibrosis.