AREG and cancer: In a recent and very exciting article published in Cell Reports, Zhang and coworkers [23] highlighted that exomeres can have a pro-neoplastic role in cancer by transferring cargo proteins with functional activities such as β-galactoside α2,6-sialyltransferase 1 and amphiregulin, which participate in cell proliferation and affect the invasiveness of cancer cells [25,26,27,28].