The time-dependent in vitro cell uptake (Figure S3) implied that the AB-Lac particles loaded with o-carborane were likely taken up by cancer cell lines through “endocytosis” because previous studies have also reported that the selective uptake of certain kinds of nanoparticles and hydrophobic cancer drugs internalized by the targeted cancer cell line were mediated by “endocytosis” [6,47]. The gene discussed is LCT; the disease is cancer.