CD8A and nonpapillary renal cell carcinoma: Early stage tumors (G1), as compared to later stage tumors (G3), not only showed a lower ercDC score, but by trend also had a lower cytotoxic infiltrate, approximated by the mean expression levels of CD8A and NKG7 (natural killer cell granule protein 7 expressed by NK cells and CD8 T cells in ccRCC [22]) (Figure 8E,G).