Our confocal observations that VEGFR2 is decreased in STZ neuroretina, particularly in the GCL, confirmed by NeuN/VEGFR2 labelled RGCs and the related VEGFR2 integrated density and VEGFR2 percentage area analyses (Figure 5), support previous evidence that this cell population is highly vulnerable to diabetes in the early stages of the pathology [38,39]. The gene discussed is RBFOX3; the disease is diabetes mellitus.