IL33 and atopic eczema: Moreover, in a mouse model of allergic dermatitis, increased IL-33 in sensitized skin caused neutrophil infiltration and a high expression of IL-4, IL-17a, CXCL1, and CXCL2, but not IFN-γ; additionally, the proinflammatory factors promote virus replication and inflammation after incubated with vaccinia virus, which is involved in Eczema Vaccinatum [184].