NAMPT and neoplasm: Although a specific receptor for visfatin has not been described, it has been shown to induce tumor cell proliferation by promoting cellular survival through NF-κB/Notch1, AKT/GSK-3β/β-catenin, c-Abl/STAT3, AKT/ERK1/2, and acetylated SIRT1/p53, and by promoting the G1 to S transition of the cell cycle [56,64,65,66,67,68,69,70].