DNMT3A and laryngotracheoesophageal cleft: Although anti-DNMT3A autoantibody were found elevated in the LC compared to the HCC group, however, no significant differences were found between HCC and NHS groups in anti-DNMT3A or HSP60 autoantibodies, suggesting that these two autoantibodies might not be applicable for Asian HCC diagnosis, and they might be the exclusive diagnostic biomarkers for Hispanic HCC.