PPARG and cardiac hypertrophy: Quercetin lowered the blood pressure level and, remarkably, minimized the left-ventricular-to-body-weight (LVW/BW) ratio in hypertensive rats, while in vitro experiments suggested the suppression of transcription activity of AP-1 (c-fos, c-jun) protein (typically involved in cardiac hypertrophy) in H9C2 cells by PPAR-γ activation by quercetin [117].