Genes also involved in NMSCs pathogenesis are melanocortin-1 receptor (MC1R), xeroderma pigmentosum complementation group C (XPC), cytochrome P450 2D6 (CYP2D6), cyclin dependent kinase inhibitor 2A (CDKN2A), glutathione S-transferase theta 1 gene (GSTT1), and telomerase [20,23]. This evidence concerns the gene CYP2D6 and Xeroderma pigmentosum complementation group C.