RB1 and retinoblastoma: Measuring mitochondrial respiration parameters revealed low basal mitochondrial respiration, maximal respiration and spare respiration in RB1-over-expressed WERI-Rb1 (Figure 1A–C), Y79 (Figure 1D–F) and GL1-RB1 (Figure 1G–I), further highlighting an altered mitochondrial function and energy profile in retinoblastoma cells with RB1 complementation.