IDH1 and central nervous system cancer: Gliomas with IDH mutations tended to show a higher ADCmin (IDH-mutated = 1.11 ± 0.21; IDH-wildtype = 0.82 ± 0.13; p < 0.05) and a lower maximum FA (IDH-mutated = 0.23 ± 0.10; IDH-wildtype = 0.30 ± 0.07; p < 0.05) [57] (Table 2).