IL6 and Stroke: As evident from our data, RIC therapy alone in diabetic stroke unexpectedly augmented the inflammatory gene expressions significantly as compared to the stroke control group when analyzed for IL-6 (p = 0.0001), IL-1β (p = 0.0002), iCAM-1 (p = 0.030), and iNOS (p = 0.021) at 6 h post-stroke (Figure 7).