IGHE and airway hyperresponsiveness: In conclusion, FAGS and CK showed anti-asthmatic effects such as reduction in the following: airway hyperresponsiveness, IgE, inflammation, mucus production, collagen accumulation, Th2 IL, histamine, tryptase, calcium, ROS, MDA, cell death, macrophage infiltration, ER stress and ferroptosis signals, and iron accumulation in an OVA-exposed allergic mouse model.