LINC-PINT and type 2 diabetes mellitus: Moreover, the overexpression and the silencing of LINC-PINT results in an increase or reduction, respectively, of the viability of HG-treated ARPE-19 and AC16 cells [159], suggesting that the reduction of LINC-PINT may favor the progression of cardiomyopathy and retinopathy in subjects with T2D [159].