AKT1 and diabetes mellitus: Network pharmacology supported by in silico studies revealed that there are nearly 36 different metabolites in D. erecta that modulate up to 31 different targets and pathways involved in the pathogenesis of diabetes, with tyrosine phosphatase 1B and phosphatidylinositol 3-kinase-protein kinase B (PI3K-AKT) being the chiefly regulated target and pathway, respectively [25].